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Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus–Infected Hepatocytes During Interferon Administration
Capsid allosteric modulators (CAMs) inhibit the encapsidation of hepatitis B virus (HBV) pregenomic RNA (pgRNA), which contains a pathogen‐associated molecular pattern motif. However, the effect of CAMs on the innate immune response of HBV‐infected hepatocytes remains unclear, and we examined this e...
Autores principales: | Fukutomi, Keisuke, Hikita, Hayato, Murai, Kazuhiro, Nakabori, Tasuku, Shimoda, Akiyoshi, Fukuoka, Makoto, Yamai, Takuo, Higuchi, Yuichiro, Miyakawa, Kei, Suemizu, Hiroshi, Ryo, Akihide, Yamada, Ryoko, Kodama, Takahiro, Sakamori, Ryotaro, Tatsumi, Tomohide, Takehara, Tetsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793994/ https://www.ncbi.nlm.nih.gov/pubmed/34558845 http://dx.doi.org/10.1002/hep4.1804 |
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