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Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus–Infected Hepatocytes During Interferon Administration

Capsid allosteric modulators (CAMs) inhibit the encapsidation of hepatitis B virus (HBV) pregenomic RNA (pgRNA), which contains a pathogen‐associated molecular pattern motif. However, the effect of CAMs on the innate immune response of HBV‐infected hepatocytes remains unclear, and we examined this e...

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Detalles Bibliográficos
Autores principales: Fukutomi, Keisuke, Hikita, Hayato, Murai, Kazuhiro, Nakabori, Tasuku, Shimoda, Akiyoshi, Fukuoka, Makoto, Yamai, Takuo, Higuchi, Yuichiro, Miyakawa, Kei, Suemizu, Hiroshi, Ryo, Akihide, Yamada, Ryoko, Kodama, Takahiro, Sakamori, Ryotaro, Tatsumi, Tomohide, Takehara, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793994/
https://www.ncbi.nlm.nih.gov/pubmed/34558845
http://dx.doi.org/10.1002/hep4.1804

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