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Activation of p53 After Irradiation Impairs the Regenerative Capacity of the Mouse Liver

Radiation therapy is one of the treatment methods for hepatocellular carcinoma. However, radiation tolerance of the liver is low, and the detailed effect of radiation on liver regeneration has not been clarified. C57BL/6J mice or hepatocyte‐specific p53 knockout (KO) mice (albumin [Alb]‐Cre Trp53(fl...

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Detalles Bibliográficos
Autores principales:	Urabe, Makiko, Hikita, Hayato, Saito, Yoshinobu, Kudo, Shinnosuke, Fukumoto, Kenji, Mizutani, Naoki, Myojin, Yuta, Doi, Akira, Sato, Katsuhiko, Sakane, Sadatsugu, Makino, Yuki, Kodama, Takahiro, Sakamori, Ryotaro, Tatsumi, Tomohide, Takehara, Tetsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793995/ https://www.ncbi.nlm.nih.gov/pubmed/34585534 http://dx.doi.org/10.1002/hep4.1815

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