Induced Pluripotent Stem Cells From Subjects With Primary Sclerosing Cholangitis Develop a Senescence Phenotype Following Biliary Differentiation

Primary sclerosing cholangitis (PSC) is a chronic fibroinflammatory disease of the biliary tract characterized by cellular senescence and periportal fibrogenesis. Specific disease features that are cell intrinsic and either genetically or epigenetically mediated remain unclear due in part to a lack...

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Detalles Bibliográficos
Autores principales: Jalan‐Sakrikar, Nidhi, De Assuncao, Thiago M., Navarro‐Corcuera, Amaia, Hamdan, Feda H., Loarca, Lorena, Kirkeby, Lindsey A., Resch, Zachary T., O’Hara, Steven P., Juran, Brian D., Lazaridis, Konstantinos N., Rosen, Charles B., Heimbach, Julie K., Taner, Timucin, Shah, Vijay H., LaRusso, Nicholas F., Huebert, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793999/
https://www.ncbi.nlm.nih.gov/pubmed/34519176
http://dx.doi.org/10.1002/hep4.1809

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