Exposure to valproic acid is associated with less pulmonary infiltrates and improvements in diverse clinical outcomes and laboratory parameters in patients hospitalized with COVID-19

BACKGROUND: Valproic acid (VPA) has shown beneficial effects in vitro against SARS-CoV-2 infection, but no study has analyzed its efficacy in the clinical setting. METHODS: This multicenter, retrospective study included 165 adult patients receiving VPA at the time of admission to hospital, and 330 c...

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Detalles Bibliográficos
Autores principales: Collazos, Julio, Domingo, Pere, Fernández-Araujo, Nerio, Asensi-Díaz, Elia, Vilchez-Rueda, Helem, Lalueza, Antonio, Roy-Vallejo, Emilia, Blanes, Rosa, Raya-Cruz, Manuel, Sanz-Cánovas, Jaime, Artero, Arturo, Ramos-Rincón, José-Manuel, Dueñas-Gutiérrez, Carlos, Lamas-Ferreiro, José Luis, Asensi, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794166/
https://www.ncbi.nlm.nih.gov/pubmed/35085321
http://dx.doi.org/10.1371/journal.pone.0262777

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