Family-based whole-exome sequencing identifies rare variants potentially related to cutaneous melanoma predisposition in Brazilian melanoma-prone families

Genetic predisposition accounts for nearly 10% of all melanoma cases and has been associated with a dozen moderate- to high-penetrance genes, including CDKN2A, CDK4, POT1 and BAP1. However, in most melanoma-prone families, the genetic etiology of cancer predisposition remains undetermined. The goal...

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Detalles Bibliográficos
Autores principales: Fidalgo, Felipe, Torrezan, Giovana Tardin, de Sá, Bianca Costa Soares, Barros, Bruna Durães de Figueiredo, Moredo, Luciana Facure, Valieris, Renan, de Souza, Sandro J., Duprat, João Pereira, Krepischi, Ana Cristina Victorino, Carraro, Dirce Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794197/
https://www.ncbi.nlm.nih.gov/pubmed/35085295
http://dx.doi.org/10.1371/journal.pone.0262419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794197/
https://www.ncbi.nlm.nih.gov/pubmed/35085295
http://dx.doi.org/10.1371/journal.pone.0262419

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