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CXCR4 Knockdown Via CRISPR/CAS9 in a Tumor-Associated Macrophage Model Decreases Human Breast Cancer Cell Migration

Introduction Breast cancer is the leading cause of cancer-related deaths in women worldwide with the majority of deaths due to metastasis. The development of metastasis is closely related to the tumor microenvironment where tumor-associated macrophages (TAMs) are the main immune cell component playi...

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Detalles Bibliográficos
Autores principales: Jaramillo-Valverde, Luis, Levano, Kelly S, Capristano, Silvia, Tarazona, David D, Cisneros, Alberto, Yufra-Picardo, Velia M, Valdivia-Silva, Julio, Guio, Heinner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794389/
https://www.ncbi.nlm.nih.gov/pubmed/35111484
http://dx.doi.org/10.7759/cureus.20842