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E-cadherin activating antibodies limit barrier dysfunction and inflammation in mouse inflammatory bowel disease

Deficits in gastrointestinal (GI) paracellular permeability has been implicated in etiology of Inflammatory Bowel Disease (IBD), and E-cadherin, a key component of the epithelial junctional complex, has been implicated in both barrier function and IBD. We have previously described antibodies against...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Chirosree, Schecterson, Leslayann, Gumbiner, Barry M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794503/
https://www.ncbi.nlm.nih.gov/pubmed/34402758
http://dx.doi.org/10.1080/21688370.2021.1940741