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Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner

DNA double strand breaks (DSBs) have been highly studied in the context of cancers, as DSBs can lead to apoptosis or tumorigenesis. Several pharmaceuticals are widely used to target DSBs during cancer therapy. Amifostine (WR-2721) and etoposide are two commonly used drugs: amifostine reduces DSBs, w...

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Detalles Bibliográficos
Autores principales: Boutros, Sydney Weber, Krenik, Destine, Holden, Sarah, Unni, Vivek K., Raber, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794536/
https://www.ncbi.nlm.nih.gov/pubmed/35106123
http://dx.doi.org/10.18632/oncotarget.28180

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