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Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report

Squamous cell carcinoma (SCC) of the hypopharynx is associated with the worst prognosis of all squamous cell cancer types of the head and neck, with a rich submucosal lymphatic network and a significant inferior extent. Generally, cancers of the head and neck have a big impact on the quality of life...

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Autores principales: Vulcu Cordunianu, Alina-Georgiana, Ganea, Gabriel, Cordunianu, Mihai Alexandru, Cochior, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794550/
https://www.ncbi.nlm.nih.gov/pubmed/35126698
http://dx.doi.org/10.3892/etm.2022.11118
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author Vulcu Cordunianu, Alina-Georgiana
Ganea, Gabriel
Cordunianu, Mihai Alexandru
Cochior, Daniel
author_facet Vulcu Cordunianu, Alina-Georgiana
Ganea, Gabriel
Cordunianu, Mihai Alexandru
Cochior, Daniel
author_sort Vulcu Cordunianu, Alina-Georgiana
collection PubMed
description Squamous cell carcinoma (SCC) of the hypopharynx is associated with the worst prognosis of all squamous cell cancer types of the head and neck, with a rich submucosal lymphatic network and a significant inferior extent. Generally, cancers of the head and neck have a big impact on the quality of life (QoL) in patients, both before and after treatment, due to the fact that most cases are diagnosed in advanced stages, with lymph node metastases and have an aggressive pattern associated with low survival rates. The present case report aimed to see the evolution of a patient successfully treated for hypopharyngeal cancer with conservation therapies from the QoL perspective and the influence made by the presence of tracheostomy. Variables, including clinical parameters (sex, age, TNM classification, performance status, histological type and tumor subsite), local control, QoL, Adult Comorbidity Evaluation-27 score and overall survival were assessed, according to the American Joint Committee on Cancer 8th edition, for a 58-year-old patient treated with conservation therapies and tracheostomy in a tertiary center. Subjective features measured through the QoL questionnaire had scores with lowering tendencies during the treatment period. The patient was provided with early training for tracheostomy care and early discharge education. The following objective features of treatment response were exhibited: Hemoglobin levels, leukocyte count, tumor size, imagistic evaluations and local control to confirm treatment response. It is essential when planning the treatment of aggressive and rare pathologies, such as hypopharyngeal cancer, to consider the QoL and patient choice for better adherence. Overall, the results demonstrated that the initial requirement for emergency tracheostomy was not associated with any ulterior complications and did not influence the end result of the treatment.
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spelling pubmed-87945502022-02-03 Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report Vulcu Cordunianu, Alina-Georgiana Ganea, Gabriel Cordunianu, Mihai Alexandru Cochior, Daniel Exp Ther Med Articles Squamous cell carcinoma (SCC) of the hypopharynx is associated with the worst prognosis of all squamous cell cancer types of the head and neck, with a rich submucosal lymphatic network and a significant inferior extent. Generally, cancers of the head and neck have a big impact on the quality of life (QoL) in patients, both before and after treatment, due to the fact that most cases are diagnosed in advanced stages, with lymph node metastases and have an aggressive pattern associated with low survival rates. The present case report aimed to see the evolution of a patient successfully treated for hypopharyngeal cancer with conservation therapies from the QoL perspective and the influence made by the presence of tracheostomy. Variables, including clinical parameters (sex, age, TNM classification, performance status, histological type and tumor subsite), local control, QoL, Adult Comorbidity Evaluation-27 score and overall survival were assessed, according to the American Joint Committee on Cancer 8th edition, for a 58-year-old patient treated with conservation therapies and tracheostomy in a tertiary center. Subjective features measured through the QoL questionnaire had scores with lowering tendencies during the treatment period. The patient was provided with early training for tracheostomy care and early discharge education. The following objective features of treatment response were exhibited: Hemoglobin levels, leukocyte count, tumor size, imagistic evaluations and local control to confirm treatment response. It is essential when planning the treatment of aggressive and rare pathologies, such as hypopharyngeal cancer, to consider the QoL and patient choice for better adherence. Overall, the results demonstrated that the initial requirement for emergency tracheostomy was not associated with any ulterior complications and did not influence the end result of the treatment. D.A. Spandidos 2022-03 2022-01-05 /pmc/articles/PMC8794550/ /pubmed/35126698 http://dx.doi.org/10.3892/etm.2022.11118 Text en Copyright: © Cordunianu et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Vulcu Cordunianu, Alina-Georgiana
Ganea, Gabriel
Cordunianu, Mihai Alexandru
Cochior, Daniel
Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report
title Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report
title_full Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report
title_fullStr Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report
title_full_unstemmed Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report
title_short Quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: A case report
title_sort quality of life and tracheostomy influence in successfully treated hypopharyngeal cancer: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794550/
https://www.ncbi.nlm.nih.gov/pubmed/35126698
http://dx.doi.org/10.3892/etm.2022.11118
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