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Downregulation of PIK3CB Involved in Alzheimer's Disease via Apoptosis, Axon Guidance, and FoxO Signaling Pathway

OBJECTIVE: To investigate the molecular function of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta (PIK3CB) underlying Alzheimer's disease (AD). METHODS: RNA sequencing data were used to filtrate differentially expressed genes (DEGs) in AD/nondementia control and PIK3CB-l...

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Detalles Bibliográficos
Autores principales: Zhou, Zhike, Bai, Jun, Zhong, Shanshan, Zhang, Rongwei, Kang, Kexin, Zhang, Xiaoqian, Xu, Ying, Zhao, Chuansheng, Zhao, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794666/
https://www.ncbi.nlm.nih.gov/pubmed/35096262
http://dx.doi.org/10.1155/2022/1260161