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Downregulation of PIK3CB Involved in Alzheimer's Disease via Apoptosis, Axon Guidance, and FoxO Signaling Pathway
OBJECTIVE: To investigate the molecular function of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta (PIK3CB) underlying Alzheimer's disease (AD). METHODS: RNA sequencing data were used to filtrate differentially expressed genes (DEGs) in AD/nondementia control and PIK3CB-l...
Autores principales: | Zhou, Zhike, Bai, Jun, Zhong, Shanshan, Zhang, Rongwei, Kang, Kexin, Zhang, Xiaoqian, Xu, Ying, Zhao, Chuansheng, Zhao, Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794666/ https://www.ncbi.nlm.nih.gov/pubmed/35096262 http://dx.doi.org/10.1155/2022/1260161 |
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