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BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring
BACKGROUND: The burden of cardiovascular diseases (CVDs) is increasing substantially due to population growth and aging. Determining effective prevention and understanding the underlying mechanisms remain desirable pursuits for increasing the quality of life. As centenarians and their offspring may...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794670/ https://www.ncbi.nlm.nih.gov/pubmed/35096109 http://dx.doi.org/10.1155/2022/3836247 |
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author | Hai, Peng-Cheng Yao, Dong-Xiao Zhao, Rui Dong, Chen Saymuah, Sara Pan, Yue-Song Gu, Zhi-Feng Wang, Yi-Long Wang, Chen Gao, Jian-Lin |
author_facet | Hai, Peng-Cheng Yao, Dong-Xiao Zhao, Rui Dong, Chen Saymuah, Sara Pan, Yue-Song Gu, Zhi-Feng Wang, Yi-Long Wang, Chen Gao, Jian-Lin |
author_sort | Hai, Peng-Cheng |
collection | PubMed |
description | BACKGROUND: The burden of cardiovascular diseases (CVDs) is increasing substantially due to population growth and aging. Determining effective prevention and understanding the underlying mechanisms remain desirable pursuits for increasing the quality of life. As centenarians and their offspring may have genetic advantages, they may present with healthier cardiovascular-related profiles. METHODS: We launched a cross-sectional household-based survey of centenarian families, including 253 centenarians, 217 centenarian offspring, and 116 offspring spouses without centenarian parents from county-level Chinese longevity city Rugao. Among offspring and offspring spouses were the following arrangements: 101 paired offspring and offspring spouses who lived together, 116 unpaired offspring, and 16 unpaired spouses. We investigated their cardiovascular-related health status including waist circumference, body mass index (BMI), blood pressure, and plasma lipids and compared results among centenarians, centenarian offspring, and offspring spouses. RESULTS: Centenarians ranged from 99 to 109 years with a median age of 100 years. Centenarian offspring, with a median age of 70 years, and offspring spouses, with a median age of 69 years, shared similar age. Results of blood pressure, plasma lipid levels, and BMI displayed no significant difference between centenarian offspring and offspring spouses. However, centenarians appeared to have lower waist circumference, BMI, TC, LDL-C, TG, and diastolic blood pressure but higher levels of systolic blood pressure (p < 0.05). Multivariate analysis showed the prevalence of obesity, hypertension, and dyslipidemia was similar between centenarian offspring and offspring spouses, while centenarians appeared to have a lower prevalence of obesity and a higher prevalence of hypertension (p < 0.05). CONCLUSIONS: Centenarians and centenarian offspring did not present healthier BMI, blood pressure, or plasma lipids than offspring spouses. Further research on longevity and cardiovascular diseases are desirable. |
format | Online Article Text |
id | pubmed-8794670 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-87946702022-01-28 BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring Hai, Peng-Cheng Yao, Dong-Xiao Zhao, Rui Dong, Chen Saymuah, Sara Pan, Yue-Song Gu, Zhi-Feng Wang, Yi-Long Wang, Chen Gao, Jian-Lin Evid Based Complement Alternat Med Research Article BACKGROUND: The burden of cardiovascular diseases (CVDs) is increasing substantially due to population growth and aging. Determining effective prevention and understanding the underlying mechanisms remain desirable pursuits for increasing the quality of life. As centenarians and their offspring may have genetic advantages, they may present with healthier cardiovascular-related profiles. METHODS: We launched a cross-sectional household-based survey of centenarian families, including 253 centenarians, 217 centenarian offspring, and 116 offspring spouses without centenarian parents from county-level Chinese longevity city Rugao. Among offspring and offspring spouses were the following arrangements: 101 paired offspring and offspring spouses who lived together, 116 unpaired offspring, and 16 unpaired spouses. We investigated their cardiovascular-related health status including waist circumference, body mass index (BMI), blood pressure, and plasma lipids and compared results among centenarians, centenarian offspring, and offspring spouses. RESULTS: Centenarians ranged from 99 to 109 years with a median age of 100 years. Centenarian offspring, with a median age of 70 years, and offspring spouses, with a median age of 69 years, shared similar age. Results of blood pressure, plasma lipid levels, and BMI displayed no significant difference between centenarian offspring and offspring spouses. However, centenarians appeared to have lower waist circumference, BMI, TC, LDL-C, TG, and diastolic blood pressure but higher levels of systolic blood pressure (p < 0.05). Multivariate analysis showed the prevalence of obesity, hypertension, and dyslipidemia was similar between centenarian offspring and offspring spouses, while centenarians appeared to have a lower prevalence of obesity and a higher prevalence of hypertension (p < 0.05). CONCLUSIONS: Centenarians and centenarian offspring did not present healthier BMI, blood pressure, or plasma lipids than offspring spouses. Further research on longevity and cardiovascular diseases are desirable. Hindawi 2022-01-20 /pmc/articles/PMC8794670/ /pubmed/35096109 http://dx.doi.org/10.1155/2022/3836247 Text en Copyright © 2022 Peng-Cheng Hai et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Hai, Peng-Cheng Yao, Dong-Xiao Zhao, Rui Dong, Chen Saymuah, Sara Pan, Yue-Song Gu, Zhi-Feng Wang, Yi-Long Wang, Chen Gao, Jian-Lin BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring |
title | BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring |
title_full | BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring |
title_fullStr | BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring |
title_full_unstemmed | BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring |
title_short | BMI, Blood Pressure, and Plasma Lipids among Centenarians and Their Offspring |
title_sort | bmi, blood pressure, and plasma lipids among centenarians and their offspring |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794670/ https://www.ncbi.nlm.nih.gov/pubmed/35096109 http://dx.doi.org/10.1155/2022/3836247 |
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