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Effects of maternal diet-induced obesity on metabolic disorders and age-associated miRNA expression in the liver of male mouse offspring

OBJECTIVE: This study investigated the effect of maternal obesity on aged-male offspring liver phenotype and hepatic expression of a programmed miRNA. METHODS: A mouse model (C57BL/6 J) of maternal diet-induced obesity was used to investigate fasting-serum metabolites, hepatic lipid content, steatos...

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Detalles Bibliográficos
Autores principales: Mennitti, Laís Vales, Carpenter, Asha A. M., Loche, Elena, Pantaleão, Lucas C., Fernandez-Twinn, Denise S., Schoonejans, Josca M., Blackmore, Heather L., Ashmore, Thomas J., Pisani, Luciana Pellegrini, Tadross, John A., Hargreaves, Iain, Ozanne, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794789/
https://www.ncbi.nlm.nih.gov/pubmed/34663892
http://dx.doi.org/10.1038/s41366-021-00985-1