Case Report: Unmanipulated Matched Sibling Donor Hematopoietic Cell Transplantation In TBX1 Congenital Athymia: A Lifesaving Therapeutic Approach When Facing a Systemic Viral Infection

Congenital athymia can present with severe T cell lymphopenia (TCL) in the newborn period, which can be detected by decreased T cell receptor excision circles (TRECs) on newborn screening (NBS). The most common thymic stromal defect causing selective TCL is 22q11.2 deletion syndrome (22q11.2DS). T-b...

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Detalles Bibliográficos
Autores principales: Chitty-Lopez, Maria, Duff, Carla, Vaughn, Gretchen, Trotter, Jessica, Monforte, Hector, Lindsay, David, Haddad, Elie, Keller, Michael D., Oshrine, Benjamin R., Leiding, Jennifer W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794793/
https://www.ncbi.nlm.nih.gov/pubmed/35095830
http://dx.doi.org/10.3389/fimmu.2021.721917

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