Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures

Pseudouridine (Ψ) is a ubiquitous RNA modification incorporated by pseudouridine synthase (Pus) enzymes into hundreds of noncoding and protein-coding RNA substrates. Here, we determined the contributions of substrate structure and protein sequence to binding and catalysis by pseudouridine synthase 7...

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Detalles Bibliográficos
Autores principales: Purchal, Meredith K., Eyler, Daniel E., Tardu, Mehmet, Franco, Monika K., Korn, Megan M., Khan, Taslima, McNassor, Ryan, Giles, Rachel, Lev, Katherine, Sharma, Hari, Monroe, Jeremy, Mallik, Leena, Koutmos, Markos, Koutmou, Kristin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794802/
https://www.ncbi.nlm.nih.gov/pubmed/35058356
http://dx.doi.org/10.1073/pnas.2109708119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794802/
https://www.ncbi.nlm.nih.gov/pubmed/35058356
http://dx.doi.org/10.1073/pnas.2109708119

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