Neoadjuvant PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy in Locally Advanced Anal Canal Squamous Cell Carcinoma Patients: Antitumor Efficacy, Safety and Biomarker Analysis

BACKGROUND: Anal canal squamous cell carcinoma (ACSCC) is an exceedingly rare malignant neoplasm with challenges in sphincter preservation, treatment toxicities and long-term survival. Little is known concerning the activity of PD-1 antibodies in locally advanced ACSCC. This study reports on the eff...

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Detalles Bibliográficos
Autores principales: Xiao, WeiWei, Yuan, Yan, Wang, SuiHai, Liao, Zhidong, Cai, PeiQiang, Chen, BaoQing, Zhang, Rong, Wang, Fang, Zeng, ZhiFan, Gao, YuanHong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794813/
https://www.ncbi.nlm.nih.gov/pubmed/35095878
http://dx.doi.org/10.3389/fimmu.2021.798451

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