Tuning protein half-life in mouse using sequence-defined biopolymers functionalized with lipids

The use of biologics in the treatment of numerous diseases has increased steadily over the past decade due to their high specificities, low toxicity, and limited side effects. Despite this success, peptide- and protein-based drugs are limited by short half-lives and immunogenicity. To address these...

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Detalles Bibliográficos
Autores principales: Vanderschuren, Koen, Arranz-Gibert, Pol, Khang, Minsoo, Hadar, Dagan, Gaudin, Alice, Yang, Fan, Folta-Stogniew, Ewa, Saltzman, W. Mark, Amiram, Miriam, Isaacs, Farren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794819/
https://www.ncbi.nlm.nih.gov/pubmed/35046019
http://dx.doi.org/10.1073/pnas.2103099119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794819/
https://www.ncbi.nlm.nih.gov/pubmed/35046019
http://dx.doi.org/10.1073/pnas.2103099119

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