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Tuning protein half-life in mouse using sequence-defined biopolymers functionalized with lipids
The use of biologics in the treatment of numerous diseases has increased steadily over the past decade due to their high specificities, low toxicity, and limited side effects. Despite this success, peptide- and protein-based drugs are limited by short half-lives and immunogenicity. To address these...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794819/ https://www.ncbi.nlm.nih.gov/pubmed/35046019 http://dx.doi.org/10.1073/pnas.2103099119 |