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Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs

Submucosal glands (SMGs) protect lungs but can also contribute to disease. For example, in cystic fibrosis (CF), SMGs produce abnormal mucus that disrupts mucociliary transport. CF is an ion transport disease, yet knowledge of the ion transporters expressed by SMG acini, which produce mucus, and SMG...

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Detalles Bibliográficos
Autores principales: Yu, Wenjie, Moninger, Thomas O., Thurman, Andrew L., Xie, Yuliang, Jain, Akansha, Zarei, Keyan, Powers, Linda S., Pezzulo, Alejandro A., Stoltz, David A., Welsh, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794846/
https://www.ncbi.nlm.nih.gov/pubmed/35046051
http://dx.doi.org/10.1073/pnas.2119759119