ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis

Alveolar macrophages (AMs) are critical for lung immune defense and homeostasis. They are orchestrators of chronic obstructive pulmonary disease (COPD), with their number significantly increased and functions altered in COPD. However, it is unclear how AM number and function are controlled in a heal...

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Detalles Bibliográficos
Autores principales: Lam, Terence Y. W., Nguyen, Ngan, Peh, Hong Yong, Shanmugasundaram, Mahalakshmi, Chandna, Ritu, Tee, Jong Huat, Ong, Chee Bing, Hossain, Md. Zakir, Venugopal, Shruthi, Zhang, Tianyi, Xu, Simin, Qiu, Tao, Kong, Wan Ting, Chakarov, Svetoslav, Srivastava, Supriya, Liao, Wupeng, Kim, Jin-Soo, Teh, Ming, Ginhoux, Florent, Fred Wong, W. S., Ge, Ruowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794848/
https://www.ncbi.nlm.nih.gov/pubmed/35046017
http://dx.doi.org/10.1073/pnas.2019161119

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