A large fraction of trisomy 12, 17p(−), and 11q(−) CLL cases carry unidentified microdeletions of miR-15a/16-1

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia and is characterized by chromosomal aberrations including 13q, 11q, and 17p deletions and a trisomy of chromosome 12 (T12). 13q deletions are often associated with 11q and 17p deletions in aggressive cases. Conversely, T12 CLLs sho...

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Detalles Bibliográficos
Autores principales: Pepe, Felice, Rassenti, Laura Z., Pekarsky, Yuri, Labanowska, Jadwiga, Nakamura, Tatsuya, Nigita, Giovanni, Kipps, Thomas J., Balatti, Veronica, Croce, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794880/
https://www.ncbi.nlm.nih.gov/pubmed/35064090
http://dx.doi.org/10.1073/pnas.2118752119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794880/
https://www.ncbi.nlm.nih.gov/pubmed/35064090
http://dx.doi.org/10.1073/pnas.2118752119

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