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A large fraction of trisomy 12, 17p(−), and 11q(−) CLL cases carry unidentified microdeletions of miR-15a/16-1
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia and is characterized by chromosomal aberrations including 13q, 11q, and 17p deletions and a trisomy of chromosome 12 (T12). 13q deletions are often associated with 11q and 17p deletions in aggressive cases. Conversely, T12 CLLs sho...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794880/ https://www.ncbi.nlm.nih.gov/pubmed/35064090 http://dx.doi.org/10.1073/pnas.2118752119 |