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Spire1 and Myosin Vc promote Ca(2+)-evoked externalization of von Willebrand factor in endothelial cells

Weibel–Palade bodies (WPB) are endothelial cell-specific storage granules that regulate vascular hemostasis by releasing the platelet adhesion receptor von Willebrand factor (VWF) following stimulation. Fusion of WPB with the plasma membrane is accompanied by the formation of actin rings or coats th...

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Detalles Bibliográficos
Autores principales: Holthenrich, Anna, Terglane, Julian, Naß, Johannes, Mietkowska, Magdalena, Kerkhoff, Eugen, Gerke, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794916/
https://www.ncbi.nlm.nih.gov/pubmed/35084586
http://dx.doi.org/10.1007/s00018-021-04108-x