Use of a Clostridioides difficile Murine Immunization and Challenge Model to Evaluate Single and Combination Vaccine Adjuvants Consisting of Alum and NKT Cell-Activating Ligands

Adjuvant combinations may enhance or broaden the expression of immune responses to vaccine antigens. Information on whether established Alum type adjuvants can be combined with experimental CD1d ligand adjuvants is currently lacking. In this study, we used a murine Clostridioides difficile immunizat...

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Detalles Bibliográficos
Autores principales: Lang, Gillian A., Norman, Kaylee, Amadou Amani, Souwelimatou, Shadid, Tyler M., Ballard, Jimmy D., Lang, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794951/
https://www.ncbi.nlm.nih.gov/pubmed/35095921
http://dx.doi.org/10.3389/fimmu.2021.818734

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