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Divalent metal cations stimulate skeleton interoception for new bone formation in mouse injury models

Bone formation induced by divalent metal cations has been widely reported; however, the underlying mechanism is unclear. Here we report that these cations stimulate skeleton interoception by promoting prostaglandin E2 secretion from macrophages. This immune response is accompanied by the sprouting a...

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Detalles Bibliográficos
Autores principales: Qiao, Wei, Pan, Dayu, Zheng, Yufeng, Wu, Shuilin, Liu, Xuanyong, Chen, Zhuofan, Wan, Mei, Feng, Shiqin, Cheung, Kenneth M. C., Yeung, Kelvin W. K., Cao, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795158/
https://www.ncbi.nlm.nih.gov/pubmed/35087048
http://dx.doi.org/10.1038/s41467-022-28203-0