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Divalent metal cations stimulate skeleton interoception for new bone formation in mouse injury models
Bone formation induced by divalent metal cations has been widely reported; however, the underlying mechanism is unclear. Here we report that these cations stimulate skeleton interoception by promoting prostaglandin E2 secretion from macrophages. This immune response is accompanied by the sprouting a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795158/ https://www.ncbi.nlm.nih.gov/pubmed/35087048 http://dx.doi.org/10.1038/s41467-022-28203-0 |