Cargando…

Lentivirus- or AAV-mediated gene therapy interventions in ischemic stroke: A systematic review of preclinical in vivo studies

Due to the limited therapeutic options after ischemic stroke, gene therapy has emerged as a promising choice, especially with recent advances in viral vector delivery systems. Therefore, we aimed to provide the current state of the art of lentivirus (LV) and adeno-associated virus (AAV) mediated gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Skukan, Laura, Brezak, Matea, Ister, Rok, Klimaschewski, Lars, Vojta, Aleksandar, Zoldoš, Vlatka, Gajović, Srećko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795232/ https://www.ncbi.nlm.nih.gov/pubmed/34427147 http://dx.doi.org/10.1177/0271678X211039997

Ejemplares similares

Adaptation or Malignant Transformation: The Two Faces of Epigenetically Mediated Response to Stress
por: Vojta, Aleksandar, et al.
Publicado: (2013)

Inhibition of DNA Methylation Alters Chromatin Organization, Nuclear Positioning and Activity of 45S rDNA Loci in Cycling Cells of Q. robur
por: Bočkor, Vedrana Vičić, et al.
Publicado: (2014)

Repurposing the CRISPR-Cas9 system for targeted DNA methylation
por: Vojta, Aleksandar, et al.
Publicado: (2016)

Gene therapy of adeno‐associated virus (AAV) vectors in preclinical models of ischemic stroke
por: Wang, Jing, et al.
Publicado: (2023)

Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges
por: Maes, Margaret E., et al.
Publicado: (2019)

DNA hypomethylation upregulates expression of the MGAT3 gene in HepG2 cells and leads to changes in N-glycosylation of secreted glycoproteins
por: Klasić, Marija, et al.
Publicado: (2016)

Epigenetic Differentiation of Natural Populations of Lilium bosniacum Associated with Contrasting Habitat Conditions
por: Zoldoš, Vlatka, et al.
Publicado: (2018)

The effects of splenectomy in murine models of ischemic stroke: a systematic review and meta-analysis
por: Sternak, Marko, et al.
Publicado: (2022)

The effect of natriuretic peptides and bradykinin on development of brain oedema after ischemic stroke
por: Dobrivojević, Marina, et al.
Publicado: (2015)

Antagonistic and synergistic epigenetic modulation using orthologous CRISPR/dCas9-based modular system
por: Josipović, Goran, et al.
Publicado: (2019)

Evolutional and clinical implications of the epigenetic regulation of protein glycosylation
por: Horvat, Tomislav, et al.
Publicado: (2011)

Glycans – the third revolution in evolution
por: Lauc, Gordan, et al.
Publicado: (2014)

Personalized medicine – where do we stand?: Pouring some water into wine: a realistic perspective
por: Gundert-Remy, Ursula, et al.
Publicado: (2012)

Effects of Estradiol on Immunoglobulin G Glycosylation: Mapping of the Downstream Signaling Mechanism
por: Mijakovac, Anika, et al.
Publicado: (2021)

Microbubbles combined with ultrasound therapy in ischemic stroke: A systematic review of in-vivo preclinical studies
por: Auboire, Laurent, et al.
Publicado: (2018)

Computed microtomography visualization and quantification of mouse ischemic brain lesion by nonionic radio contrast agents
por: Dobrivojević, Marina, et al.
Publicado: (2013)

Age and the Metabolic Syndrome as Risk Factors for Ischemic Stroke: Improving Preclinical Models of Ischemic Stroke
por: Lucke-Wold, Brandon P., et al.
Publicado: (2012)

In vivo Neuroregeneration to Treat Ischemic Stroke Through NeuroD1 AAV-Based Gene Therapy in Adult Non-human Primates
por: Ge, Long-Jiao, et al.
Publicado: (2020)

Determinants of effective lentivirus-driven microRNA expression in vivo
por: Mishima, Takuya, et al.
Publicado: (2016)

Genetic and Epigenetic Association of Hepatocyte Nuclear Factor-1α with Glycosylation in Post-Traumatic Stress Disorder
por: Tudor, Lucija, et al.
Publicado: (2022)

Preclinical evidence of remote ischemic conditioning in ischemic stroke, a metanalysis update
por: Torres-Querol, Coral, et al.
Publicado: (2021)

What is constant in a time of change?
por: Gajović, Srećko
Publicado: (2011)

por: Gajović, Srećko
Publicado: (2011)

Publishing interdisciplinary research – a perspective from the Croatian Medical Journal
por: Gajović, Srećko
Publicado: (2015)

Diamond Open Access in the quest for interdisciplinarity and excellence
por: Gajović, Srećko
Publicado: (2017)

Knowledge-for-data trade at the interface between precision medicine and person-centered care
por: Gajović, Srećko
Publicado: (2018)

Resisting the small cake phenomenon – sharing resources and knowledge makes you rich
por: Gajović, Srećko
Publicado: (2017)

Independent, Publicly Funded Journals Adhering to Platinum Open Access Are the Future of Responsible Scholarly Publishing
por: Gajović, Srećko
Publicado: (2019)

Immunomodulation in Administration of rAAV: Preclinical and Clinical Adjuvant Pharmacotherapies
por: Chu, Wing Sum, et al.
Publicado: (2021)

Preclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs
por: Pleticha, Josef, et al.
Publicado: (2014)

Commentary: In vivo Neuroregeneration to Treat Ischemic Stroke Through NeuroD1 AAV-Based Gene Therapy in Adult Non-human Primates
por: Zhang, Xiaoqin, et al.
Publicado: (2021)

Manufacture of Third-Generation Lentivirus for Preclinical Use, with Process Development Considerations for Translation to Good Manufacturing Practice
por: Gándara, Carolina, et al.
Publicado: (2018)

Preclinical animal studies in ischemic stroke: Challenges and some solutions
por: Narayan, Sunil K., et al.
Publicado: (2021)

RNA packaging in lentiviruses
por: Lever, Andrew ML
Publicado: (2009)

Reactivation of corticogenesis-related transcriptional factors BCL11B and SATB2 after ischemic lesion of the adult mouse brain
por: Srakočić, Sanja, et al.
Publicado: (2023)

AAV-Mediated Gene Therapy for Choroideremia: Preclinical Studies in Personalized Models
por: Vasireddy, Vidyullatha, et al.
Publicado: (2013)

Physiopathology of ischemic stroke and its modulation using memantine: evidence from preclinical stroke
por: Martínez-Coria, Hilda, et al.
Publicado: (2020)

Multiple presence of prothrombotic risk factors in Croatian children with arterial ischemic stroke and transient ischemic attack
por: Leniček Krleža, Jasna, et al.
Publicado: (2013)

Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury
por: Bohacek, Ivan, et al.
Publicado: (2012)

Preclinical test of a lentivirus-mediated RNAi gene therapy against HIV-AIDS in the humanized mouse model
por: Centlivre, Mireille, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_d95pjpfqhn0aocq6setidjdjdc