Gene therapy of prostate cancer using liposomes containing perforin expression vector driven by the promoter of prostate-specific antigen gene

Perforin secreted from cytotoxic lymphocytes plays a critical role in cancer immunosurveillance. The aim of this study was to investigate the therapeutic potential of liposomes containing perforin expression vector driven by the promotor of prostate-specific antigen (PSA). The anti-tumor effect of p...

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Detalles Bibliográficos
Autores principales: Mizutani, Kosuke, Kawakami, Kyojiro, Fujita, Yasunori, Kato, Taku, Takai, Manabu, Kato, Daiki, Iinuma, Koji, Koie, Takuya, Ito, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795355/
https://www.ncbi.nlm.nih.gov/pubmed/35087064
http://dx.doi.org/10.1038/s41598-021-03324-6

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