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Rho GTPase gene expression and breast cancer risk: a Mendelian randomization analysis

The Rho GTPase family consists of 20 genes encoding intracellular signalling proteins that influence cytoskeletal dynamics, cell migration and cell cycle progression. They are implicated in breast cancer progression but their role in breast cancer aetiology is unknown. As aberrant Rho GTPase activit...

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Detalles Bibliográficos
Autores principales: Kazmi, Nabila, Robinson, Tim, Zheng, Jie, Kar, Siddhartha, Martin, Richard M., Ridley, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795400/
https://www.ncbi.nlm.nih.gov/pubmed/35087170
http://dx.doi.org/10.1038/s41598-022-05549-5