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Infection dynamics of COVID-19 virus under lockdown and reopening

Motivated by COVID-19, we develop and analyze a simple stochastic model for the spread of disease in human population. We track how the number of infected and critically ill people develops over time in order to estimate the demand that is imposed on the hospital system. To keep this demand under co...

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Autores principales: Svoboda, Jakub, Tkadlec, Josef, Pavlogiannis, Andreas, Chatterjee, Krishnendu, Nowak, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795434/
https://www.ncbi.nlm.nih.gov/pubmed/35087091
http://dx.doi.org/10.1038/s41598-022-05333-5
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author Svoboda, Jakub
Tkadlec, Josef
Pavlogiannis, Andreas
Chatterjee, Krishnendu
Nowak, Martin A.
author_facet Svoboda, Jakub
Tkadlec, Josef
Pavlogiannis, Andreas
Chatterjee, Krishnendu
Nowak, Martin A.
author_sort Svoboda, Jakub
collection PubMed
description Motivated by COVID-19, we develop and analyze a simple stochastic model for the spread of disease in human population. We track how the number of infected and critically ill people develops over time in order to estimate the demand that is imposed on the hospital system. To keep this demand under control, we consider a class of simple policies for slowing down and reopening society and we compare their efficiency in mitigating the spread of the virus from several different points of view. We find that in order to avoid overwhelming of the hospital system, a policy must impose a harsh lockdown or it must react swiftly (or both). While reacting swiftly is universally beneficial, being harsh pays off only when the country is patient about reopening and when the neighboring countries coordinate their mitigation efforts. Our work highlights the importance of acting decisively when closing down and the importance of patience and coordination between neighboring countries when reopening.
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spelling pubmed-87954342022-01-28 Infection dynamics of COVID-19 virus under lockdown and reopening Svoboda, Jakub Tkadlec, Josef Pavlogiannis, Andreas Chatterjee, Krishnendu Nowak, Martin A. Sci Rep Article Motivated by COVID-19, we develop and analyze a simple stochastic model for the spread of disease in human population. We track how the number of infected and critically ill people develops over time in order to estimate the demand that is imposed on the hospital system. To keep this demand under control, we consider a class of simple policies for slowing down and reopening society and we compare their efficiency in mitigating the spread of the virus from several different points of view. We find that in order to avoid overwhelming of the hospital system, a policy must impose a harsh lockdown or it must react swiftly (or both). While reacting swiftly is universally beneficial, being harsh pays off only when the country is patient about reopening and when the neighboring countries coordinate their mitigation efforts. Our work highlights the importance of acting decisively when closing down and the importance of patience and coordination between neighboring countries when reopening. Nature Publishing Group UK 2022-01-27 /pmc/articles/PMC8795434/ /pubmed/35087091 http://dx.doi.org/10.1038/s41598-022-05333-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Svoboda, Jakub
Tkadlec, Josef
Pavlogiannis, Andreas
Chatterjee, Krishnendu
Nowak, Martin A.
Infection dynamics of COVID-19 virus under lockdown and reopening
title Infection dynamics of COVID-19 virus under lockdown and reopening
title_full Infection dynamics of COVID-19 virus under lockdown and reopening
title_fullStr Infection dynamics of COVID-19 virus under lockdown and reopening
title_full_unstemmed Infection dynamics of COVID-19 virus under lockdown and reopening
title_short Infection dynamics of COVID-19 virus under lockdown and reopening
title_sort infection dynamics of covid-19 virus under lockdown and reopening
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795434/
https://www.ncbi.nlm.nih.gov/pubmed/35087091
http://dx.doi.org/10.1038/s41598-022-05333-5
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