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Cardiomyocyte IL-1R2 protects heart from ischemia/reperfusion injury by attenuating IL-17RA-mediated cardiomyocyte apoptosis

Myocardial ischemia reperfusion (I/R) injury is a complex process with intense inflammatory response and cardiomyocyte apoptosis. As a decoy receptor of IL-1β, Interleukin-1 receptor type 2 (IL-1R2) inhibits IL-1β signaling. However, its role in I/R injury remains unknown. Here we found that the ser...

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Detalles Bibliográficos
Autores principales:	Lin, Jun, Li, Qinfeng, Jin, Tingting, Wang, Jiacheng, Gong, Yingchao, Lv, Qingbo, Wang, Meihui, Chen, Jiawen, Shang, Min, Zhao, Yanbo, Fu, Guosheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795442/ https://www.ncbi.nlm.nih.gov/pubmed/35087030 http://dx.doi.org/10.1038/s41419-022-04533-1

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