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Enhanced glycolysis in granulosa cells promotes the activation of primordial follicles through mTOR signaling

In mammals, nonrenewable primordial follicles are activated in an orderly manner to maintain the longevity of reproductive life. Mammalian target of rapamycin (mTOR)-KIT ligand (KITL) signaling in pre-granulosa cells and phosphatidylinositol 3-kinase (PI3K)-protein kinase B (Akt)-forkhead Box O3a (F...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaodan, Zhang, Wenbo, Wang, Zhijuan, Zheng, Nana, Yuan, Feifei, Li, Biao, Li, Xuelan, Deng, Ling, Lin, Min, Chen, Xin, Zhang, Meijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795455/
https://www.ncbi.nlm.nih.gov/pubmed/35087042
http://dx.doi.org/10.1038/s41419-022-04541-1