Sex-specific splicing of Z- and W-borne nr5a1 alleles suggests sex determination is controlled by chromosome conformation

Pogona vitticeps has female heterogamety (ZZ/ZW), but the master sex-determining gene is unknown, as it is for all reptiles. We show that nr5a1 (Nuclear Receptor Subfamily 5 Group A Member 1), a gene that is essential in mammalian sex determination, has alleles on the Z and W chromosomes (Z-nr5a1 an...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiuwen, Wagner, Susan, Holleley, Clare E., Deakin, Janine E., Matsubara, Kazumi, Deveson, Ira W., O’Meally, Denis, Patel, Hardip R., Ezaz, Tariq, Li, Zhao, Wang, Chexu, Edwards, Melanie, Graves, Jennifer A. Marshall, Georges, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795496/
https://www.ncbi.nlm.nih.gov/pubmed/35074916
http://dx.doi.org/10.1073/pnas.2116475119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795496/
https://www.ncbi.nlm.nih.gov/pubmed/35074916
http://dx.doi.org/10.1073/pnas.2116475119

Ejemplares similares