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CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection
Early events of the retroviral life cycle are the targets of many host restriction factors that have evolved to prevent establishment of infection. Incoming retroviral DNAs are transcriptionally silenced before integration in most cell types, and efficient viral gene expression occurs only after for...
Autores principales: | Geis, Franziska K., Sabo, Yosef, Chen, Xiao, Li, Yinglu, Lu, Chao, Goff, Stephen P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795523/ https://www.ncbi.nlm.nih.gov/pubmed/35074917 http://dx.doi.org/10.1073/pnas.2116735119 |
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