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Engineered human antibodies for the opsonization and killing of Staphylococcus aureus
Gram-positive organisms with their thick envelope cannot be lysed by complement alone. Nonetheless, antibody-binding on the surface can recruit complement and mark these invaders for uptake and killing by phagocytes, a process known as opsonophagocytosis. The crystallizable fragment of immunoglobuli...
Autores principales: | Chen, Xinhai, Schneewind, Olaf, Missiakas, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795526/ https://www.ncbi.nlm.nih.gov/pubmed/35058363 http://dx.doi.org/10.1073/pnas.2114478119 |
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