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Engineered human antibodies for the opsonization and killing of Staphylococcus aureus

Gram-positive organisms with their thick envelope cannot be lysed by complement alone. Nonetheless, antibody-binding on the surface can recruit complement and mark these invaders for uptake and killing by phagocytes, a process known as opsonophagocytosis. The crystallizable fragment of immunoglobuli...

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Detalles Bibliográficos
Autores principales: Chen, Xinhai, Schneewind, Olaf, Missiakas, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795526/
https://www.ncbi.nlm.nih.gov/pubmed/35058363
http://dx.doi.org/10.1073/pnas.2114478119

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