Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite

Cells are continuously exposed to potentially dangerous compounds. Progressive accumulation of damage is suspected to contribute to neurodegenerative diseases and aging, but the molecular identity of the damage remains largely unknown. Here we report that PARK7, an enzyme mutated in hereditary Parki...

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Detalles Bibliográficos
Autores principales: Heremans, Isaac P., Caligiore, Francesco, Gerin, Isabelle, Bury, Marina, Lutz, Marilena, Graff, Julie, Stroobant, Vincent, Vertommen, Didier, Teleman, Aurelio A., Van Schaftingen, Emile, Bommer, Guido T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795555/
https://www.ncbi.nlm.nih.gov/pubmed/35046029
http://dx.doi.org/10.1073/pnas.2111338119

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