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Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal

BACKGROUND: Sexual dysfunction is a common symptom in patients with schizophrenia, especially in chronically medicated patients. However, the relationship between sexual dysfunction and emotional response to sexual arousal in male patients with schizophrenia remains unclear. This study aimed to asse...

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Autores principales: Liu, Dianying, Liu, Shaohua, Xiu, Meihong, Deng, Hongdong, Guo, Huiyun, Liu, Wanglin, Zhang, Delong, Mao, Zhongzhen, Huang, Dan, Huang, Donghua, Miao, Qiumei, Qiu, Lijuan, Zhao, Ning Olivia, Wu, Hanjing Emily, Zhang, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795612/
https://www.ncbi.nlm.nih.gov/pubmed/35095591
http://dx.doi.org/10.3389/fpsyt.2021.761598
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author Liu, Dianying
Liu, Shaohua
Xiu, Meihong
Deng, Hongdong
Guo, Huiyun
Liu, Wanglin
Zhang, Delong
Mao, Zhongzhen
Huang, Dan
Huang, Donghua
Miao, Qiumei
Qiu, Lijuan
Zhao, Ning Olivia
Wu, Hanjing Emily
Zhang, Xiangyang
author_facet Liu, Dianying
Liu, Shaohua
Xiu, Meihong
Deng, Hongdong
Guo, Huiyun
Liu, Wanglin
Zhang, Delong
Mao, Zhongzhen
Huang, Dan
Huang, Donghua
Miao, Qiumei
Qiu, Lijuan
Zhao, Ning Olivia
Wu, Hanjing Emily
Zhang, Xiangyang
author_sort Liu, Dianying
collection PubMed
description BACKGROUND: Sexual dysfunction is a common symptom in patients with schizophrenia, especially in chronically medicated patients. However, the relationship between sexual dysfunction and emotional response to sexual arousal in male patients with schizophrenia remains unclear. This study aimed to assess the incidence, risk factors of sexual dysfunction in males, and their clinical correlations to sexual arousal in male patients with schizophrenia in China. METHODS: A total of 162 male patients, aged 18–50 years, with schizophrenia were recruited from a psychiatric hospital in Ganzhou. The clinical symptoms were assessed by the Positive and Negative Syndrome Scale (PANSS). The Arizona Sexual Experience Scale was utilized to evaluate sexual dysfunction. Erotic images were selected from International Affective Picture System (IAPS). Sixty-eight out of the 162 subjects completed the erotic pictures reactivity task. RESULTS: Overall, 48 (29.6%) patients were measured as having global sexual dysfunction, 72 (44.4%) patients as having strength of sex drive dysfunction, 51 (31.5%) patients as having sexual arousal dysfunction, 55 (34.0%) patients as having penile erection dysfunction, 60 (37.0%) patients as having reached orgasm dysfunction, and 60 (37.0%) patients as having satisfaction with orgasm dysfunction. The sexual dysfunction patients had significantly higher scores on the negative symptoms of the PANSS. The only important predictor of sexual dysfunction was the severity of PANSS negative factor. The sense of pleasure and arousal post viewing erotic images in the sexual dysfunction group were lower compared to the non-sexual dysfunction group. The sense of pleasure and approach motivation were significantly negatively correlated with the severity of sexual dysfunction. CONCLUSIONS: This study shows that nearly one-third of young and middle-aged chronically medicated male inpatients with schizophrenia suffer from sexual dysfunction. The negative factor of the PANSS can be regarded as the risk factor of sexual dysfunction. Schizophrenia patients with sexual dysfunction experienced lower pleasure and higher avoidance motivation than non-sexual dysfunction patients when exposed to erotic stimuli.
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spelling pubmed-87956122022-01-29 Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal Liu, Dianying Liu, Shaohua Xiu, Meihong Deng, Hongdong Guo, Huiyun Liu, Wanglin Zhang, Delong Mao, Zhongzhen Huang, Dan Huang, Donghua Miao, Qiumei Qiu, Lijuan Zhao, Ning Olivia Wu, Hanjing Emily Zhang, Xiangyang Front Psychiatry Psychiatry BACKGROUND: Sexual dysfunction is a common symptom in patients with schizophrenia, especially in chronically medicated patients. However, the relationship between sexual dysfunction and emotional response to sexual arousal in male patients with schizophrenia remains unclear. This study aimed to assess the incidence, risk factors of sexual dysfunction in males, and their clinical correlations to sexual arousal in male patients with schizophrenia in China. METHODS: A total of 162 male patients, aged 18–50 years, with schizophrenia were recruited from a psychiatric hospital in Ganzhou. The clinical symptoms were assessed by the Positive and Negative Syndrome Scale (PANSS). The Arizona Sexual Experience Scale was utilized to evaluate sexual dysfunction. Erotic images were selected from International Affective Picture System (IAPS). Sixty-eight out of the 162 subjects completed the erotic pictures reactivity task. RESULTS: Overall, 48 (29.6%) patients were measured as having global sexual dysfunction, 72 (44.4%) patients as having strength of sex drive dysfunction, 51 (31.5%) patients as having sexual arousal dysfunction, 55 (34.0%) patients as having penile erection dysfunction, 60 (37.0%) patients as having reached orgasm dysfunction, and 60 (37.0%) patients as having satisfaction with orgasm dysfunction. The sexual dysfunction patients had significantly higher scores on the negative symptoms of the PANSS. The only important predictor of sexual dysfunction was the severity of PANSS negative factor. The sense of pleasure and arousal post viewing erotic images in the sexual dysfunction group were lower compared to the non-sexual dysfunction group. The sense of pleasure and approach motivation were significantly negatively correlated with the severity of sexual dysfunction. CONCLUSIONS: This study shows that nearly one-third of young and middle-aged chronically medicated male inpatients with schizophrenia suffer from sexual dysfunction. The negative factor of the PANSS can be regarded as the risk factor of sexual dysfunction. Schizophrenia patients with sexual dysfunction experienced lower pleasure and higher avoidance motivation than non-sexual dysfunction patients when exposed to erotic stimuli. Frontiers Media S.A. 2022-01-14 /pmc/articles/PMC8795612/ /pubmed/35095591 http://dx.doi.org/10.3389/fpsyt.2021.761598 Text en Copyright © 2022 Liu, Liu, Xiu, Deng, Guo, Liu, Zhang, Mao, Huang, Huang, Miao, Qiu, Zhao, Wu and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Liu, Dianying
Liu, Shaohua
Xiu, Meihong
Deng, Hongdong
Guo, Huiyun
Liu, Wanglin
Zhang, Delong
Mao, Zhongzhen
Huang, Dan
Huang, Donghua
Miao, Qiumei
Qiu, Lijuan
Zhao, Ning Olivia
Wu, Hanjing Emily
Zhang, Xiangyang
Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal
title Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal
title_full Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal
title_fullStr Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal
title_full_unstemmed Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal
title_short Sexual Dysfunction in Chronically Medicated Male Inpatients With Schizophrenia: Prevalence, Risk Factors, Clinical Manifestations, and Response to Sexual Arousal
title_sort sexual dysfunction in chronically medicated male inpatients with schizophrenia: prevalence, risk factors, clinical manifestations, and response to sexual arousal
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795612/
https://www.ncbi.nlm.nih.gov/pubmed/35095591
http://dx.doi.org/10.3389/fpsyt.2021.761598
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