Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells

Prostate-specific membrane antigen (PSMA) is highly overexpressed in most prostate cancers and is clinically visualized using PSMA-specific probes incorporating glutamate-ureido-lysine (GUL). PSMA is effectively absent from certain high-mortality, treatment-resistant subsets of prostate cancers, suc...

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Detalles Bibliográficos
Autores principales: Bakht, Martin K., Hayward, John J., Shahbazi-Raz, Farsheed, Skubal, Magdalena, Tamura, Ryo, Stringer, Keith F., Meister, Daniel, Venkadakrishnan, Varadha Balaji, Xue, Hui, Pillon, Adam, Stover, Mathew, Tronchin, Adam, Fifield, Bre-Anne, Mader, Lavleen, Ku, Sheng-Yu, Cheon, Gi Jeong, Kang, Keon Wook, Wang, Yuzhuo, Dong, Xuesen, Beltran, Himisha, Grimm, Jan, Porter, Lisa A., Trant, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795759/
https://www.ncbi.nlm.nih.gov/pubmed/35064078
http://dx.doi.org/10.1073/pnas.2025710119

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