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MFG-E8 Maintains Cellular Homeostasis by Suppressing Endoplasmic Reticulum Stress in Pancreatic Exocrine Acinar Cells

Excessive endoplasmic reticulum (ER) stress contributes significantly to the pathogenesis of exocrine acinar damage in acute pancreatitis. Our previous study found that milk fat globule EGF factor 8 (MFG-E8), a lipophilic glycoprotein, alleviates acinar cell damage during AP via binding to αvβ3/5 in...

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Detalles Bibliográficos
Autores principales: Ren, Yifan, Liu, Wuming, Zhang, Jia, Bi, Jianbin, Fan, Meng, Lv, Yi, Wu, Zheng, Zhang, Yuanyuan, Wu, Rongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795834/
https://www.ncbi.nlm.nih.gov/pubmed/35096831
http://dx.doi.org/10.3389/fcell.2021.803876

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