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MFG-E8 Maintains Cellular Homeostasis by Suppressing Endoplasmic Reticulum Stress in Pancreatic Exocrine Acinar Cells
Excessive endoplasmic reticulum (ER) stress contributes significantly to the pathogenesis of exocrine acinar damage in acute pancreatitis. Our previous study found that milk fat globule EGF factor 8 (MFG-E8), a lipophilic glycoprotein, alleviates acinar cell damage during AP via binding to αvβ3/5 in...
Autores principales: | Ren, Yifan, Liu, Wuming, Zhang, Jia, Bi, Jianbin, Fan, Meng, Lv, Yi, Wu, Zheng, Zhang, Yuanyuan, Wu, Rongqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795834/ https://www.ncbi.nlm.nih.gov/pubmed/35096831 http://dx.doi.org/10.3389/fcell.2021.803876 |
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