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Molecular Dosimetry of DNA Adducts in Rats Exposed to Vinyl Acetate Monomer

Vinyl acetate monomer (VAM) is heavily used to synthesize polymers. Previous studies have shown that inhaled VAM, being metabolized to acetaldehyde, may form DNA adducts including N(2)-ethylidene-deoxyguanosine (N(2)-EtD-dG), which may subsequently cause mutations and contribute to its carcinogenesi...

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Detalles Bibliográficos
Autores principales:	Hsiao, Yun-Chung, Liu, Chih-Wei, Hoffman, Gary, Fang, Caroline, Lu, Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Molecular, Biochemical, and Systems Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795904/ https://www.ncbi.nlm.nih.gov/pubmed/34904679 http://dx.doi.org/10.1093/toxsci/kfab140

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