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TRPM2 Is Not Required for T-Cell Activation and Differentiation

Antigen recognition by the T-cell receptor induces a cytosolic Ca(2+) signal that is crucial for T-cell function. The Ca(2+) channel TRPM2 (transient receptor potential cation channel subfamily M member 2) has been shown to facilitate influx of extracellular Ca(2+) through the plasma membrane of T c...

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Detalles Bibliográficos
Autores principales: Lory, Niels C., Nawrocki, Mikolaj, Corazza, Martina, Schmid, Joanna, Schumacher, Valéa, Bedke, Tanja, Menzel, Stephan, Koch-Nolte, Friedrich, Guse, Andreas H., Huber, Samuel, Mittrücker, Hans-Willi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795911/
https://www.ncbi.nlm.nih.gov/pubmed/35095852
http://dx.doi.org/10.3389/fimmu.2021.778916