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Platelet-Derived Growth Factor-BB Inhibits Intervertebral Disc Degeneration via Suppressing Pyroptosis and Activating the MAPK Signaling Pathway

Platelet-derived growth factor-BB (PDGF-BB) is a cytokine involved in tissue repair and tumor progression. It has been found to have expression differences between normal and degenerative intervertebral discs. However, it is not clear whether PDGF-BB has a protective effect on intervertebral disc de...

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Detalles Bibliográficos
Autores principales: Zhang, Weikang, Gong, Yuhang, Zheng, Xiaohang, Qiu, Jianxin, Jiang, Ting, Chen, Lihua, Lu, Fangying, Wu, Xinhui, Cheng, Fengmin, Hong, Zhenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795915/
https://www.ncbi.nlm.nih.gov/pubmed/35095507
http://dx.doi.org/10.3389/fphar.2021.799130