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Efficacy of Plinabulin vs Pegfilgrastim for Prevention of Docetaxel-Induced Neutropenia in Patients With Solid Tumors: A Randomized Clinical Trial

IMPORTANCE: Prevention of chemotherapy-induced neutropenia (CIN) and its clinical consequences is an unmet need for which plinabulin, a selective immunomodulating microtubule-binding agent, is being tested. OBJECTIVE: To demonstrate noninferiority between plinabulin and pegfilgrastim for days of sev...

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Detalles Bibliográficos
Autores principales: Blayney, Douglas W., Mohanlal, Ramon, Adamchuk, Hryhoriy, Kirtbaya, Dmitry Valikovich, Chen, Michael, Du, Lihua, Ogenstad, Stephan, Ginn, Greg, Huang, Lan, Zhang, Qingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796017/
https://www.ncbi.nlm.nih.gov/pubmed/35084480
http://dx.doi.org/10.1001/jamanetworkopen.2021.45446