Autophagy Targeting and Hematological Mobilization in FLT3-ITD Acute Myeloid Leukemia Decrease Repopulating Capacity and Relapse by Inducing Apoptosis of Committed Leukemic Cells

SIMPLE SUMMARY: One of the most frequent molecular anomalies in acute myeloid leukemia (AML) is the mutation of the fms-like receptor tyrosine kinase 3 through internal tandem duplications, giving rise to a constitutive proliferative signaling. Even though clinical trials have shown that targeting t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dupont, Marine, Huart, Mathilde, Lauvinerie, Claire, Bidet, Audrey, Guitart, Amélie Valérie, Villacreces, Arnaud, Vigon, Isabelle, Desplat, Vanessa, El Habhab, Ali, Pigneux, Arnaud, Ivanovic, Zoran, Brunet De la Grange, Philippe, Dumas, Pierre-Yves, Pasquet, Jean-Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796021/
https://www.ncbi.nlm.nih.gov/pubmed/35053612
http://dx.doi.org/10.3390/cancers14020453

Ejemplares similares

Ejemplares similares