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Principles of mRNA targeting via the Arabidopsis m(6)A-binding protein ECT2

Specific recognition of N6-methyladenosine (m(6)A) in mRNA by RNA-binding proteins containing a YT521-B homology (YTH) domain is important in eukaryotic gene regulation. The Arabidopsis YTH domain protein ECT2 is thought to bind to mRNA at URU(m(6)A)Y sites, yet RR(m(6)A)CH is the canonical m(6)A co...

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Detalles Bibliográficos
Autores principales: Arribas-Hernández, Laura, Rennie, Sarah, Köster, Tino, Porcelli, Carlotta, Lewinski, Martin, Staiger, Dorothee, Andersson, Robin, Brodersen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796052/
https://www.ncbi.nlm.nih.gov/pubmed/34591015
http://dx.doi.org/10.7554/eLife.72375