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Protective Effect of Mesenchymal Stem Cells on Isolated Islets Survival and Against Hypoxia Associated With the HIF-1α/PFKFB3 Pathway
Islets have a high demand for oxygen and most of them will die of hypoxia injury before and after transplantation. Hypoxic damage is one of the key factors associated with islet graft dysfunction. Mesenchymal stem cells (MSCs) have multiple functions and can enhance the therapeutic effect of islet t...
Autores principales: | Wei, Lingling, Zhang, Lijie, Yang, Longyan, Wang, Xin, Zhao, Chunhua, Zhao, Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796103/ https://www.ncbi.nlm.nih.gov/pubmed/35045747 http://dx.doi.org/10.1177/09636897211073127 |
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