Cargando…

A Predictor Combining Clinical and Genetic Factors for AML1-ETO Leukemia Patients

Core Binding Factor (CBF)-AML is one of the most common somatic mutations in acute myeloid leukemia (AML). t(8;21)/AML1-ETO-positive acute myeloid leukemia accounts for 5-10% of all AMLs. In this study, we consecutively included 254 AML1-ETO patients diagnosed and treated at our institute from Decem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Min, Zhao, Bide, Wang, Jinghan, Zhang, Yi, Hu, Chao, Liu, Lixia, Qin, Jiayue, Lou, Feng, Cao, Shanbo, Wang, Chengcheng, Yu, Wenjuan, Tong, Hongyan, Meng, Haitao, Huang, Jian, Zhu, Honghu, Jin, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796117/ https://www.ncbi.nlm.nih.gov/pubmed/35096581 http://dx.doi.org/10.3389/fonc.2021.783114

Ejemplares similares

AML1-ETO-Related Fusion Circular RNAs Contribute to the Proliferation of Leukemia Cells
por: Wang, Ying, et al.
Publicado: (2022)

CALCRL Gene is a Suitable Prognostic Factor in AML/ETO(+) AML Patients
por: Wang, Rongrong, et al.
Publicado: (2022)

Prognostic Value of AML1/ETO Fusion Transcripts in Patients with Acute Myelogenous Leukemia
por: Cho, Eun Kyung, et al.
Publicado: (2003)

Targeted Next-Generation Sequencing of Circulating Tumor DNA, Bone Marrow, and Peripheral Blood Mononuclear Cells in Pediatric AML
por: Ruan, Min, et al.
Publicado: (2021)

The clinical impact of IKZF1 mutation in acute myeloid leukemia
por: Zhang, Xiang, et al.
Publicado: (2023)

FACSorting help to analyze a rare case of acute myeloid leukemia with concurrent AML1‐ETO and PML‐RARA
por: Chen, Man, et al.
Publicado: (2021)

Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia
por: Dou, Liping, et al.
Publicado: (2019)

Minimal residual disease monitoring via AML1-ETO breakpoint tracing in childhood acute myeloid leukemia
por: Chen, Xiaoyan, et al.
Publicado: (2021)

Amyloid precursor protein has clinical and prognostic significance in AML1-ETO-positive acute myeloid leukemia
por: Yu, Guopan, et al.
Publicado: (2018)

Oncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML
por: Mu, Guangfu, et al.
Publicado: (2020)

Successful Outcome of a Case of Acute Myeloid Leukemia with t(8;21)/AML-ETO Following Langerhans Cell Histiocytosis
por: Meng, Guangqiang, et al.
Publicado: (2019)

Heterodimerization of AML1/ETO with CBFβ is required for leukemogenesis but not for myeloproliferation
por: Thiel, V N, et al.
Publicado: (2017)

AML1/ETO sensitizes via TRAIL acute myeloid leukemia cells to the pro-apoptotic effects of hypoxia
por: Barbetti, V, et al.
Publicado: (2013)

KDM4B promotes acute myeloid leukemia associated with AML1‐ETO by regulating chromatin accessibility
por: Ueda, Takeshi, et al.
Publicado: (2021)

ABL1 kinase as a tumor suppressor in AML1-ETO and NUP98-PMX1 leukemias
por: Golovine, Konstantin, et al.
Publicado: (2023)

AML1/ETO Oncoprotein Is Directed to AML1 Binding Regions and Co-Localizes with AML1 and HEB on Its Targets
por: Gardini, Alessandro, et al.
Publicado: (2008)

A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals context-dependent binding and regulation of target genes and opposite functions in cell differentiation
por: Zhang, Yi-Fan, et al.
Publicado: (2022)

Time- and residue-specific differences in histone acetylation induced by VPA and SAHA in AML1/ETO-positive leukemia cells
por: Barbetti, Valentina, et al.
Publicado: (2013)

Celastrol Induces Cell Apoptosis and Inhibits the Expression of the AML1-ETO/C-KIT Oncoprotein in t(8;21) Leukemia
por: Yu, Xianjun, et al.
Publicado: (2016)

TAF1 plays a critical role in AML1-ETO driven leukemogenesis
por: Xu, Ye, et al.
Publicado: (2019)

The Graft-Versus-Leukemia Effect in AML
por: Sweeney, Connor, et al.
Publicado: (2019)

Acute myeloid leukemia in an 86-year-old man with AML1/ETO treated with Homoharringtonine and Arsenic Trioxide: A case report
por: He, Zhipeng, et al.
Publicado: (2019)

Clonal evolution of AML1-ETO coexisting with BCR-ABL and additional chromosome abnormalities in a blastic transformation of chronic myeloid leukemia
por: Ma, Cheng-Cheng, et al.
Publicado: (2020)

A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis
por: Sun, Xiao-Jian, et al.
Publicado: (2013)

Development and evaluation of LAMP, CPA and IMSA methods for rapid detection of the AML1/ETO fusion gene in acute myeloid leukemia
por: Yang, Zhigang, et al.
Publicado: (2018)

Gene mutation profile and risk stratification in AML1-ETO-positive acute myeloid leukemia based on next-generation sequencing
por: Yu, Guopan, et al.
Publicado: (2019)

Chidamide-based 3-drug combination regimen reverses molecular relapse post transplantation in AML1-ETO–positive acute myeloid leukemia
por: Xi, Yang, et al.
Publicado: (2023)

Oral Realgar-Indigo Naturalis Formula Plus Retinoic Acid for Acute Promyelocytic Leukemia
por: Lou, Yinjun, et al.
Publicado: (2021)

An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells
por: Zaidi, Sayyed K., et al.
Publicado: (2017)

AML1/ETO and its function as a regulator of gene transcription via epigenetic mechanisms
por: Rejeski, Kai, et al.
Publicado: (2021)

Spectrum and clinical features of gene mutations in Chinese pediatric acute lymphoblastic leukemia
por: Shen, Diying, et al.
Publicado: (2023)

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells
por: Trombly, Daniel J, et al.
Publicado: (2015)

Combined use of interferon alpha-1b, interleukin-2, and thalidomide to reverse the AML1-ETO fusion gene in acute myeloid leukemia
por: Mi, Ruihua, et al.
Publicado: (2021)

Homoharringtonine combined with aclarubicin and cytarabine synergistically induces apoptosis in t(8;21) leukemia cells and triggers caspase‐3‐mediated cleavage of the AML1‐ETO oncoprotein
por: Cao, Jiang, et al.
Publicado: (2016)

MicroRNA let-7b downregulates AML1-ETO oncogene expression in t(8;21) AML by targeting its 3′UTR
por: Johnson, Daniel T., et al.
Publicado: (2021)

RUNX1-ETO: Attacking the Epigenome for Genomic Instable Leukemia
por: van der Kouwe, Emiel, et al.
Publicado: (2019)

A Histone Acetyltransferase p300 Inhibitor C646 Induces Cell Cycle Arrest and Apoptosis Selectively in AML1-ETO-Positive AML Cells
por: Gao, Xiao-ning, et al.
Publicado: (2013)

Editorial: Acute myeloid leukemia (AML): Is it time for MRD-driven treatment?
por: Guolo, Fabio, et al.
Publicado: (2022)

Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML)
por: Agrawal, Mridul, et al.
Publicado: (2019)

AML1-ETO Inhibits Maturation of Multiple Lymphohematopoietic Lineages and Induces Myeloblast Transformation in Synergy with ICSBP Deficiency
por: Schwieger, Maike, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_gca8ek5rc1lq8hhkt84eibqpso