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Prevalence of insertion sequence elements in plasmids relating to mgrB gene disruption causing colistin resistance in Klebsiella pneumoniae

Colistin is a last resort antibiotic for the treatment of carbapenemase producing Klebsiella pneumoniae. The disruption of the mgrB gene by insertion sequences (ISs) is a mechanism mediating colistin resistance. Plasmids encode mobilizable IS elements which integrate into the mgrB gene in K. pneumon...

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Detalles Bibliográficos
Autores principales:	Fordham, Stephen Mark Edward, Mantzouratou, Anna, Sheridan, Elizabeth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796155/ https://www.ncbi.nlm.nih.gov/pubmed/35212479 http://dx.doi.org/10.1002/mbo3.1262

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