Spike-Dependent Opsonization Indicates Both Dose-Dependent Inhibition of Phagocytosis and That Non-Neutralizing Antibodies Can Confer Protection to SARS-CoV-2

Spike-specific antibodies are central to effective COVID19 immunity. Research efforts have focused on antibodies that neutralize the ACE2-Spike interaction but not on non-neutralizing antibodies. Antibody-dependent phagocytosis is an immune mechanism enhanced by opsonization, where typically, more b...

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Detalles Bibliográficos
Autores principales: Bahnan, Wael, Wrighton, Sebastian, Sundwall, Martin, Bläckberg, Anna, Larsson, Olivia, Höglund, Urban, Khakzad, Hamed, Godzwon, Magdalena, Walle, Maria, Elder, Elisabeth, Strand, Anna Söderlund, Happonen, Lotta, André, Oscar, Ahnlide, Johannes Kumra, Hellmark, Thomas, Wendel-Hansen, Vidar, Wallin, Robert PA., Malmstöm, Johan, Malmström, Lars, Ohlin, Mats, Rasmussen, Magnus, Nordenfelt, Pontus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796240/
https://www.ncbi.nlm.nih.gov/pubmed/35095897
http://dx.doi.org/10.3389/fimmu.2021.808932

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