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Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study

OBJECTIVE: To analyse and compare the clinical outcomes between patients ≥80 years and 65–79 years, who presented to our emergency department (ED) with the two most common gastric emergency (GE) clinical presentation, that is, gastric bleeding and gastric perforation. DESIGN: Single-centre retrospec...

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Autores principales: Rosa, Fausto, Covino, Marcello, Fransvea, Pietro, Cozza, Valerio, Quero, Giuseppe, Fiorillo, Claudio, Simeoni, Benedetta, La Greca, Antonio, Sganga, Gabriele, Gasbarrini, Antonio, Franceschi, Francesco, Costamagna, Guido, Alfieri, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796243/
https://www.ncbi.nlm.nih.gov/pubmed/35078851
http://dx.doi.org/10.1136/bmjopen-2021-056981
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author Rosa, Fausto
Covino, Marcello
Fransvea, Pietro
Cozza, Valerio
Quero, Giuseppe
Fiorillo, Claudio
Simeoni, Benedetta
La Greca, Antonio
Sganga, Gabriele
Gasbarrini, Antonio
Franceschi, Francesco
Costamagna, Guido
Alfieri, Sergio
author_facet Rosa, Fausto
Covino, Marcello
Fransvea, Pietro
Cozza, Valerio
Quero, Giuseppe
Fiorillo, Claudio
Simeoni, Benedetta
La Greca, Antonio
Sganga, Gabriele
Gasbarrini, Antonio
Franceschi, Francesco
Costamagna, Guido
Alfieri, Sergio
author_sort Rosa, Fausto
collection PubMed
description OBJECTIVE: To analyse and compare the clinical outcomes between patients ≥80 years and 65–79 years, who presented to our emergency department (ED) with the two most common gastric emergency (GE) clinical presentation, that is, gastric bleeding and gastric perforation. DESIGN: Single-centre retrospective cohort study. PARTICIPANTS: A total of 1011 patients were enrolled: 421 patients aged ≥80 years were compared with a group of 590 patients aged 65–79 years. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was to compare the overall mortality. Secondary outcomes included major complications, in-hospital length of stay (LOS) and need for surgical procedures. RESULTS: Patients ≥80 years with GE had different presentations at ED compared with younger patients: they had higher gastrointestinal bleeding (24.9% vs 16.3%, p=0.001), anemisation (14.5% vs 8.8%, p=0.005) and shock (10.9% vs 5.1%, p=0.001) rates. Median LOS, cumulative major complications and mortality rates were similar among the two groups. Multivariate analysis identified shock, gastric malignancy and gastric fistula as independent predictors for survival. CONCLUSIONS: Patients ≥80 years with GE did not have a higher mortality rate and cumulative major complications as compared to younger elderly patients. Invasive treatments were not associated with a different prognosis in this age group.
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spelling pubmed-87962432022-02-07 Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study Rosa, Fausto Covino, Marcello Fransvea, Pietro Cozza, Valerio Quero, Giuseppe Fiorillo, Claudio Simeoni, Benedetta La Greca, Antonio Sganga, Gabriele Gasbarrini, Antonio Franceschi, Francesco Costamagna, Guido Alfieri, Sergio BMJ Open Gastroenterology and Hepatology OBJECTIVE: To analyse and compare the clinical outcomes between patients ≥80 years and 65–79 years, who presented to our emergency department (ED) with the two most common gastric emergency (GE) clinical presentation, that is, gastric bleeding and gastric perforation. DESIGN: Single-centre retrospective cohort study. PARTICIPANTS: A total of 1011 patients were enrolled: 421 patients aged ≥80 years were compared with a group of 590 patients aged 65–79 years. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was to compare the overall mortality. Secondary outcomes included major complications, in-hospital length of stay (LOS) and need for surgical procedures. RESULTS: Patients ≥80 years with GE had different presentations at ED compared with younger patients: they had higher gastrointestinal bleeding (24.9% vs 16.3%, p=0.001), anemisation (14.5% vs 8.8%, p=0.005) and shock (10.9% vs 5.1%, p=0.001) rates. Median LOS, cumulative major complications and mortality rates were similar among the two groups. Multivariate analysis identified shock, gastric malignancy and gastric fistula as independent predictors for survival. CONCLUSIONS: Patients ≥80 years with GE did not have a higher mortality rate and cumulative major complications as compared to younger elderly patients. Invasive treatments were not associated with a different prognosis in this age group. BMJ Publishing Group 2022-01-25 /pmc/articles/PMC8796243/ /pubmed/35078851 http://dx.doi.org/10.1136/bmjopen-2021-056981 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Gastroenterology and Hepatology
Rosa, Fausto
Covino, Marcello
Fransvea, Pietro
Cozza, Valerio
Quero, Giuseppe
Fiorillo, Claudio
Simeoni, Benedetta
La Greca, Antonio
Sganga, Gabriele
Gasbarrini, Antonio
Franceschi, Francesco
Costamagna, Guido
Alfieri, Sergio
Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study
title Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study
title_full Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study
title_fullStr Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study
title_full_unstemmed Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study
title_short Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study
title_sort gastric emergencies in older adults: not always the same old story! a tertiary care emergency department observational cohort study
topic Gastroenterology and Hepatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796243/
https://www.ncbi.nlm.nih.gov/pubmed/35078851
http://dx.doi.org/10.1136/bmjopen-2021-056981
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