A CRISPR toolbox for generating intersectional genetic mouse models for functional, molecular, and anatomical circuit mapping

BACKGROUND: The functional understanding of genetic interaction networks and cellular mechanisms governing health and disease requires the dissection, and multifaceted study, of discrete cell subtypes in developing and adult animal models. Recombinase-driven expression of transgenic effector alleles...

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Detalles Bibliográficos
Autores principales: Lusk, Savannah J., McKinney, Andrew, Hunt, Patrick J., Fahey, Paul G., Patel, Jay, Chang, Andersen, Sun, Jenny J., Martinez, Vena K., Zhu, Ping Jun, Egbert, Jeremy R., Allen, Genevera, Jiang, Xiaolong, Arenkiel, Benjamin R., Tolias, Andreas S., Costa-Mattioli, Mauro, Ray, Russell S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796356/
https://www.ncbi.nlm.nih.gov/pubmed/35086530
http://dx.doi.org/10.1186/s12915-022-01227-0

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